Study on changes in Ryodoraku test according to carbon monoxide concentration in exhaled breath

Jin Suk Koo; Koo, Jin Suk

doi:10.13048/jkm.20004

JKM > Volume 41(1); 2020 > Article

Koo: Study on changes in Ryodoraku test according to carbon monoxide concentration in exhaled breath

Original Article

The Journal of Korean Medicine 2020; 41(1): 45-54.

Published online: March 9, 2020

DOI: https://doi.org/10.13048/jkm.20004

Study on changes in Ryodoraku test according to carbon monoxide concentration in exhaled breath

Jin Suk Koo^*

Division of Horticulture & Medicinal Plant, Andong National Univ. Andong, Republic of Korea

Correspondence to: 구진숙 경상북도 안동시 경동로 1375 안동대학교 생명과학대학 원예생약융합학부, Tel: +82-54-820-5845, Fax: +82-54-820-6252, E-mail: kimkoo1114@anu.ac.kr

Received February 4, 2020 Revised February 26, 2020 Accepted February 27, 2020

Abstract

Objectives

The aim of this study was to investigate relationships between Ryodoraku and carbon monoxide concentration during expiration of smokers.

This study was designed as an exploratory observational study. This study was based on the hypothesis that increased levels of carbon monoxide in the smoker’s breath may affect indicators that reflect the respiratory and circulatory systems in the Ryodoraku test.

Methods

The participants were 49 people who smoked for over a year. They were examined at least one hour after their last smoking. They were tested in a stable state. When examining carbon monoxide during expiration, they breathed deeply, kept breathing for 20 seconds, and slowly exhaled. The Ryodoraku test was performed on its representative points of twelve meridians. Pearson’s correlation analysis was used to investigate correlation between the concentration of carbon monoxide in the breath and the current in the measurement points.

Results

The higher the carbon monoxide concentration in the exhalation, the significantly greater the current value of Lt H1·both H2·Lt H3·Rt H5, deviation of Lt H1·Lt H2·Lt H3 current value and the laterality between right and left current of H3.

Conclusion

The more cigarette smoked, the more changes in heart, lung, pericardium and triple energizer meridians were observed in the Ryodoraku test. I found that increased carbon monoxide in smokers could affect the results of the Ryodoraku test.

Keywords: Ryodoraku, carbon monoxide, smoking

Table 1

Point of Measurement with Ryodoraku

Meridian	H1	H2	H3	H4	H5	H6
Organ	Lung	Pericardium	Heart	Small Intestine	Triple energizer	Large Intestine
Acupoint	태연(LU9)	대릉(PC7)	신문(HT7)	양곡(SI5)	양지(TE4)	양계(LI5)

Meridian	F1	F2	F3	F4	F5	F6

Organ	Spleen	Liver	Kidney	Bladder	Gallbladder	Stomach
Acupoint	태백(SP3)	태충(LR3)	태계(KI3)	속골(BL65)	구허(GB40)	충양ST42)

Table 2

General Characteristics of Subjects and Carbon Monoxide Levels in Exhalation(N=49)

Variables	Categories	n(%)
Age	3rd decade	14(28.6)
	4th decade	12(24.5)
	5th decade	4(8.2)
	6th decade	11(22.4)
	>60	8(16.3)

Carbon Monoxide in Exhalation (ppm)	0–5	13(26.5)
	6–10	12(25.5)
	11–15	14(28.6)
	16–20	5(8.2)
	20–37	5(8.2)

Table 3

Pearson’s correlation coefficient

		Age
CO (ppm)	Correlation coefficient	0.339*
	p-value	0.017
	N	49

* p < 0.05

Table 4

Pearson’s correlation coefficient

		CH1 (Lt)	DH1(Lt)
CO (ppm)	Correlation coefficient	0.375^**	0.361*
	p-value	0.008	0.011
	N	49	49

* p < 0.05

CH1 means current value on representative point of H1 ryodoraku

DH1 means current deviation on representative point of H1 ryodoraku

Table 5

Pearson’s correlation coefficient

		CH2 (Rt)	CH2 (Lt)	DH2 (Lt)
CO (ppm)	Correlation coefficient	0.359^*	0.390**	0.388**
	p-value	0.011	0.006	0.006
	N	49	49	49

** p < 0.01

CH2 means current value on representative point of H2 ryodoraku

DH2 means current deviation on representative point from current average of H2 ryodoraku

Table 6

Pearson’s correlation coefficient

		LH3	CH3 (Lt)	DH3 (Lt)
CO (ppm)	Correlation coefficient	0.396**	0.372**	0.331*
	p-value	0.005	0.009	0.020
	N	49	49	49

* p < 0.05

** p < 0.01

LH3 means current laterality of Lt and Rt H3 rhodoraku

CH3 means current value on representative point of H3 ryodoraku

DH3 means current deviation on representative point from current average of H3 ryodoraku

Table 7

Pearson’s correlation coefficient

		CH5 (Rt)
CO (ppm)	Correlation coefficient	0.282*
	p-value	0.050
	N	49

* p < 0.05

CH5 means current value on representative point of H5 ryodoraku

참고문헌

1. David MB, Kasper DL, Braunwald E, Fauci A, Hauser S, Longo D, Jameson JL, editors. Harrison’s principles of internal medicine. 15th ed. Columbus. McGrawHill;(2001). p. 2574-7.

2. Who Expert Committee. Smoking control strategies in developing contries. Geneva. World Health Organization;(1983.

3. Choi, HL. Smoking Cessation Program. Kor J of Family Medicine, (1993). 14(6), 396-405.

4. US Department of Helath and Human Service (USDHHS). The Health Consequences of Smoking. A Report of the Surgeon Genaral. Rockvile (MD). (2004.

5. Song, HL, & Kim, CH. Epidemiology of Smoking-Related Diseases in Korea. Kor J of Family Medicine, (2008). 29, 563-71.

6. Jung, HS, Kim, MJ, & Kim, HC. Recognition of Osteoporosis in ancient Chinese literature. J Kor Medical Classics, (2011). 24(6), 125-30.

7. Kim, IS. Smoking and Health. J Kor Med Sci, (1987). 30(8), 825-30.

8. Tobacco. 2019. May. 17. http://www.who.int/news-room/fast-sheets/detail/tabacco

9. West FS, Todd WR. Textbook of biochemistry. New York. The Macmillan Company;(1962.

10. Kim YS. Indoor environmental science. Seoul. Min-eumsa;(1995). p. 157-8. p. 545

11. Lim, BK, Kim, SW, Kang, JH, & Yang, YJ. Smoking status and expired carbon monoxide concentration. Kor J Family Med, (2001). 22(5), 674-82.

12. Jarvis, MJ, Russell, MA, & Saloojee, Y. Expired aircarbon monoxide: a simple breath test of tobacco smoke intake. British Med J, (1980). 281, 484-85.

13. Becona, E, & Vazquez, FL. Self-reported smoking and measurement of expired air carbon monoxide in aclinical treatment. Psychological Reports, (1998). 83, 316-18.

14. Benowitz, NL. The use of biologic fluid samples in assessing tobacco smoke consumption. National Institute of Drug Abuse, (1983). 6-26.

15. Lerman, C, Orleans, CT, & Engstrom, PF. Biological markers in smoking cessation treatment. Seminar in Oncology, (1993). 20, 359-67.

16. Park, YB. The Principle of Yangdorak and Its Clinical Utilization. Third medicine, (1996). 1(2), 83-94.

17. Jang, GS, Na, CS, & So, CH. Measurement of Qi Induced by the Needle Insertion on LI4, LI11 Accupoint using the Oriental Medicine Instruments. Integr Med Res, (1995). 1(1), 159-78.

18. Oh, SJ, Park, YJ, & Park, YB. Studies on thecharacteristics of the Yin-Yang, Heat-Cold by the Yangdorak patterns. J Kor Instit Orient Med Diagnosis, (2003). 8(1), 86-108.

19. Bang, JK, Park, YC, Lee, SH, Chang, DI, & Lee, YH. The study on the characteristics of Yangdorak in the patients with idiopathic parkinson’s disease. J of Kor Acupuncture, (2006). 23(6), 153-64.

20. Hwang, JH, Jung, SY, & Jung, SK. The diagnostic values of Ryodoraku and pulse analysis for respiratory disease patients. Kor J Orient Int Med, (2007). 28(3), 560-9.

21. Kim, ES, Lee, JM, Lee, CH, Cho, JH, Jang, JB, & Lee, KS. A study on characters of Yangdorak in climacteric women. J Orient Obstet Gynecol, (2008). 21(4), 159-68.

22. Kim, KS, Chung, SH, Kim, SS, & Lee, JS. The study on the characteristics of Ryodoraku score in the chronic low back pain patients. J Korean Med Rehab, (2009). 19(1), 145-54.

23. Kim, WH, & Kim, JW. A study on Bian Zhenganalysis of Bi Wi disease patient by Yangdorak diagnosis system. J Dong-Eui Orient Med, (2000). 33, 127-46.

24. Moon, YH, Bae, HS, Moon, SK, Ko, CN, Kim, YS, & Cho, KH. Clinical investigation about the interrelationship between differentiation of syndroms and numerical value of measurement (Yang-do-rack diagnosis) in acute stroke patients. Korean J Orient Int Med, (1998). 19(2), 28-36.

25. Oh, MJ, Shim, YS, & Song, HS. Sasang constitutional diagnosis by portable Ryodoraku device:comparative study with QSCC II questionnaire. J of Kor Acupuncture, (2013). 30(4), 161-7.

26. Lee, CH, Lee, GY, & Song, BG. A Study on Yangdorak Changes in Pregnant Women More than 30 Weeks Pregnant. Kor J of Oriental Gynecology, (1999). 12(1), 14-21.

27. Gellert, C, Schottker, B, & Brenner, H. Smoking and all-cause mortality in older people: systematic review and metaanalysis. Arch Intern Med, (2012). 172, 837-44.

28. The Korea National Statistical Office. Cancer Statistics, (2003). http://www.nso.go.kr

29. Kim IS. Did you know? Toxification of tobacco. Seoul. Korea Non-smoking Council;(1991.

30. Kim, IS. Smoking and health. Korean Medical Association, (1989). 30, 8.

31. Vogt, TM, Selvin, S, Widdowson, G, & Hulley, SB. Expired air carbon monoxide and serum thiocyanate as objective measures of cigarette exposure. Am J Public Health, (1977). 67, 545-9.

32. Vesey, CJ, Saloojee, Y, Cole, PV, & Russel, MAH. Carboxyhemoglobin, Plasma thiocyanate and cigarette consumption : Implication for epidemiological studies in smokers. Br Med J, (1982). 284,

33. Saloojee, Y, Vesey, CJ, Cole, PV, & Russel, MAH. Carboxyhemoglobin, plasma thiocyanate : Complementary indicators of smoking behavior. Thorax, (1982). 37, 521-5.

34. Jarvis, MJ, Phil, M, Tunstall-Pedoe, H, Feyerabend, C, Vedey, C, & Saloojee, Y. Comparison of tests used to distinguish smokers from nonsmoker. Am J Public Health, (1987). 77(11), 1435-8.

35. Wildox, RG, Hughes, J, & Roland, J. Verification of smoking history using history using urinary nicotine and cotinine measurements. Br Med J, (1979). 2, 1026-8.

36. Harley, NJ, Axelrad, MS, & Tilton, BS. Validation of self-reported smoking behavior : Biochemical analysis of cotinine and thiocyanate. Am J Public Health, (1983). 73, 1204-7.

37. Hughes, JR, Frederiksen, LW, & Frazier, MA. Carbon monoxide analyzer for measurement of smoking behavior. Behavior Therapy, (1978). 9, 293-6.

38. Jarvis, MJ, Russell, MAH, & Saloojee, Y. Expired air carbon monoside : simple breath test of tobacco smoke intake. Br Med J, (1980). 281, 484-5.

39. Jarvis, MJ, Belcher, M, & Vesey, C. Low cost carbon monoxide monitor in smoking assessment. Thorax, (1986). 41, 886-7.

40. Wald, NJ, Idle, M, & Boreham, J. Carbon monoxide in breath in relation to smoking and carboxyhemoglobin level. Thorax, (1981). 36, 366-9.

41. Jee, SH, Yun, JE, Park, JY, Sul, JW, & Kim, IS. Smoking and cause of death in Korea: 11 years follow-up prospective study. Korean J Epidemiol, (2005). 27, 182-90.

42. Bae, J, Gwack, J, Park, SK, Shin, HR, Chang, SH, & Yoo, KY. Cigarette smoking, alcohol consumption, tuberculosis and risk of lung cancer: the Kor multi-center cancer cohort study. J Prev Med Public Health, (2007). 40(4), 321-8.

43. Bae, JM, Lee, MS, Shin, MH, Kim, DH, Li, ZM, & Ahn, YO. Cigarette smoking and risk of lung cancer in Korean men: the seoul male cancer cohort study. J Kor Med Sci, (2007). 22, 508-12.

44. Jee, SH, Park, J, Jo, I, Lee, J, Yun, S, & Yun, JE. Smoking and atherosclerotic cardiovascular disease in women with lower levels of serum cholesterol. Atherosclerosis, (2007). 190, 306-12.

45. Khang, YH, Lynch, JW, Jung-Choi, K, & Cho, HJ. Explanining age-specific inequalities in mortality from all causes, cardiovascular disease and ischemic heart disease among South Korean male public servants: relative and absolute perspectives. Heart, (2008). 94, 75-82.

46. Oh, SJ, Park, YJ, & Park, YB. Studies on thecharacteristics of the Yin-Yang, Heat-Cold bythe Yangdorak patterns. J Korea Instit Orient Med Diagn, (2003). 8(1), 86-108.

47. Park, YB. The Principle of Yangdorak and Its Clinical Utilization. Third medicine, (1996). 1(2), 83-94.

48. Kyunghee University School of Oriental Medicine 45th Graduation Preparation Committee. Practical approach to diagnosis of oriental medicine. Seoul. Iljungsa;(1997). 202-4:p. 213-25.

49. Wen Su; the Integrated Research Publication Committee. Su Wen research integration. Daegu. Venus Printer;(2001). p. 297

50. Ling Shu Research integrated publication committee. Ling Shu Research integration. Daegu. Cheongwoon Printing;(2006). p. 346-50.

51. Kim, JC, Zo, EH, & Bang, JK. Study on Jinsatak (陳士鐸)’s theory of Simpo(心包) J. Oriental Medical Classics, (2010). 23(2), 141-55.

52. Baik, ES, Kim, HI, Kim, JH, Yoon, EK, Kim, SH, & Park, CH. A Study on the Relation of Pathologic Mechanisms of Samcho in Hwangdineijing and Samcho-Sanghwa. J Korean Medical Classics, (2016). 29(2), 187-202.