Trends in research on the efficacy of herbal medicines for particular matter-induced asthma focused on Pubmed

Article information

J Korean Med. 2023;44(3):163-169

Publication date (electronic) : 2023 September 1

doi : https://doi.org/10.13048/jkm.23039

¹Department of Pathology, College of Korean Medicine, Sangji University

²Research Institute of Korean Medicine, Sangji Univeristy

Correspondence to: Bo-In Kwon, Department of Pathology, College of Korean Medicine, Sangji University, 83 Sangjidae-gil, Wonju-si, Gangwon-do 26339, Republic of Korea, Tel: +82-33-730-0662, Fax: +82 33 730 0654, E-mail: kbi34812@sangji.ac.kr

Received 2023 May 11; Revised 2023 July 5; Accepted 2023 August 17.

Abstract

Objectives

This study aimed to review the experimental research trends in asthma caused by particulate matter to conduct further researches, especially in clinical trials.

Methods

We searched for the meaningful literature using medicinal herb for asthma through the Pubmed databases.

Results

Finally, six studies were finally selected. These studies showed recent trends, from 2018 to 2021 and conducted mostly in South Korea. The type of fine dust and the method of inducing asthma are different for each paper, but the effective mechanism is relatively common. It was commonly confirmed that the ratio and number of eosinophils, th2 cells and related cytokines are decreased in BALF and lung tissue by administration of medicinal herb.

Conclusions

Although the method of inducing asthma using fine dust has not yet been standardized, it is thought that more meaningful evaluation results can be derived if a standardized animal model is established in the future. Nevertheless, based on the results that herbal medicine is effective for particular matter induced asthma, it is expected that it will be the basis for expanding into future clinical studies.

Keywords: Particular matter; asthma; airway inflammation; experimental research trends; medicinal herb

Fig. 1

Prisma flow diagram of study selection process for this systematic review

Table 1

Search strategy for MEDLINE

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Article information Continued

Fig. 1

Prisma flow diagram of study selection process for this systematic review

Table 1

Search strategy for MEDLINE

Number	Search terms
1	Fine Dust
2	Particulate Matter^*
3	OR #1-2
4	herbal medicine[MeSH Terms]
5	drugs, chinese herbal[MeSH Terms]
6	medicine, kampo[MeSH Terms]
7	medicine, korean traditional[MeSH Terms]
8	ethnopharmacology[MeSH Terms]
9	herbal medicine
10	medicinal plant^*
11	traditional medicine
12	phytomedicine
13	herbal drug^*
14	herbal preparation^*
15	herbs medicinal
16	herb medicine
17	plants extracts
18	plants, medicinal
19	Chinese medicine
20	decoction
21	OR #4-20
21	#3 AND #21