Two Cases of Adult Atopic Dermatitis Improved by Administration of Osuyu-tang

Article information

J Korean Med. 2023;44(1):88-98
Publication date (electronic) : 2023 March 1
doi : https://doi.org/10.13048/jkm.23008
1Department of Korean Medicine Ophthalmology, Otolaryngology and Dermatology, Wonkwang University Korean Medicine Hospital, Iksan, Jeollabuk-do, Republic of Korea
2Midas Korean Medicine Clinic, Seoul, Republic of Korea
3Department of Acupuncture and Moxibustion, Wonkwang University Korean Medicine Hospital, Deokjingu, Jeonju, Jeollabuk-do, Republic of Korea
4Research Center of Traditional Korean Medicine, Wonkwang University, Iksan, Jeollabuk-do, Republic of Korea
Correspondence to: Eun-Heui Jo, Department of Acupuncture & Moxibustion Medicine, Wonkwang University Korean Medicine Hospital 99, Garyeonsan-ro, Deokjin-gu, Jeonju-si, Jeollabuk-do, 54887, Republic of Korea, Tel: +82-63-270-1022, Fax: +82-63-270-1199; E-mail: freezo@wonkwang.ac.kr
Corresponding author: Min-Cheol Park, Department of Korean Medicine Ophthalmology, Otolaryngology and Dermatology, Wonkwang University, Korean Medicine Hospital, 895 Muwang-ro, Iksan-si, Jeollabuk-do, 54538, Republic of Korea, Tel: +82-63-859-2821, Fax: +82-63-841-0033, E-mail: spinx11@wonkwang.ac.kr
Received 2022 July 29; Revised 2022 August 24; Accepted 2023 February 14.

Abstract

Objectives

This study is to report two cases of adult atopic dermatitis improved by Osuyu-tang.

Methods

Osuyu-tang was prescribed to two adult atopic dermatitis patients. The patients took Osuyu-tang 3 times a day for 45 days and 50 days, respectively.

Results

In case 1 who complained of redness, erythema, edema, exudation, dryness, erosion, lichenification, scaly, and pruritus, skin symptoms improved from 15 to 2, and pruritus also improved from NRS 8 to 2. In case 2 who complained of redness-centered skin symptoms, skin symptoms improved from 15 to 1, and pruritus also improved from NRS 9 to 1.

Conclusions

When Osuyu-tang was prescribed to two patients with adult atopic dermatitis, significant improvement was observed. It is thought that Osyyu-tang can be used as the treatment of other similar diseases in the future.

Fig. 1

Treatment Timeline

Fig. 2

Clinical Progress of Atopic Dermatitis

Fig. 3

Treatment Timeline

Fig. 4

Clinical Progress of Atopic Dermatitis

Symptom Evaluation Index

Prescription of Osuyu-tang (Wuzhuyu-tang)

Systematic Examination

Systematic Examination

Symptom Progress of Atopic Dermatitis

References

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Article information Continued

Fig. 1

Treatment Timeline

Fig. 2

Clinical Progress of Atopic Dermatitis

Fig. 3

Treatment Timeline

Fig. 4

Clinical Progress of Atopic Dermatitis

Table 1

Symptom Evaluation Index

Symptom Severity
Objective
Symptoms
Redness
Swelling
Oozing
Dryness
Excoriation
Lichenification
Scale
0=Absence
1=Mild
2=Moderate
3=Severe
Subjective
Symptoms
Pruritus
Sleep Loss
0 (None) ~ 10 (Severe)

Table 2

Prescription of Osuyu-tang (Wuzhuyu-tang)

Name of Natural Medicine (Herbal Medicine) Weight(g)
吳茱萸 Tetradium ruticarpum (A. Juss.) T.G. Hartley 3
生薑 Zingiber officinale Roscoe 6
大棗 Ziziphus jujuba var. inermis (Bunge) Rehder 4
人蔘 Panax ginseng C.A. Mey. 3

Total Amount 16

Table 3

Systematic Examination

大便 대변을 하루 1번 정도 시원하게 본다.
小便 소변을 시원하게 잘 본다.
寒熱 더위를 못 참는다. 얼굴에서 열이 나는 것 같다. 손발이 차갑다.
汗出 땀이 잘 나지 않는다. 사우나 가거나 운동할 때만 땀이 난다.
食慾 입맛이 좋다. 골고루 잘 먹는다. 요즘 살이 빠지고 있다.
消化 소화가 잘 된다. 배에서 소리가 자주 난다.
睡眠 잠을 잘 잔다. 잠이 많은 편이다. 할 일이 있어도 체력이 받쳐주지 않는다.
口渴 생수, 차, 음료수, 우유, 커피 다 포함해서 하루에 1ℓ 가량의 액체를 마신다.
頭部 피곤하거나 신경 쓰면 몸 어딘가가 자주 떨린다.
皮膚 피부가 잘 빨개진다. 피부가 건조하다.

Table 5

Systematic Examination

大便 하루 1–2번 정도 대변을 본다. 하루라도 변을 보지 못하면 무척 불편하다. 변을 보고 난 후 어딘가 모르게 시원하지 않다. 변이 굳다. 아랫배에 가스가 잘 찬다.
小便 소변을 시원하게 잘 본다.
寒熱 추위를 못 참는다. 더위를 못 참는다. 손발이 차갑다.
汗出 땀이 잘 나지 않는다. 사우나 가거나 운동할 때만 땀이 난다. 가슴, 겨드랑이에만 땀이 난다.
食慾 입맛이 좋다. 음식을 잘 먹는다.
消化 속이 자주 쓰리다. 배가 자주 아프다. 트림을 자주 한다.
睡眠 잠을 잘 자지 못한다. 자다가 자주 깨어난다.
口渴 따뜻한 물이 좋다. 생수, 차, 음료수, 우유, 커피 다 포함해서 하루에 1.5ℓ 가량의 액체를 마신다.
胸部 목-가슴이 조이는 옷은 답답해서 싫다.
皮膚 피부 트러블이 잘 생긴다. 피부가 건조하다.
頭面 목에 무언가 걸려있는 느낌이 들 때가 자주 있다.

Table 6

Symptom Progress of Atopic Dermatitis

2017.03.30 2017.05.25 2017.08.09
Subjective
Symptoms
Redness 3 1 1
Swelling 1 1 0
Oozing 2 1 0
Dryness 3 1 0
Excoriation 2 1 0
Lichenification 2 1 0
Scale 2 1 0

Objective
Symptoms
Pruritus 9 4 1
Sleep Loss 8 3 1

Total 32 14 3