Clinical Effectiveness of Ikgibohyeol-tang(Yìqìbǔxuè-tāng) and Deer Antler on Fatigue Symptoms and HRV Results in Outpatients at Korean Medical Hospital: A Retrospective Chart Review Study

Article information

J Korean Med. 2022;43(3):139-149

Publication date (electronic) : 2022 September 1

doi : https://doi.org/10.13048/jkm.22036

Won Jung Ha ¹

, Sang-Kwan Moon ^1,2

, Han-Gyul Lee ^1,2

, Seung-Yeon Cho ^1,2

, Seong-Uk Park ^1,2

, Woo-sang Jung ^1,2

, Jung-Mi Park ^1,2

, Chang-Nam Ko ^1,2

, Ki-Ho Cho ^1,2

, Seungwon Kwon ^1,2^,

¹Dept. of Clinical Korean Medicine, Graduate school, Kyung-Hee University

^1,2Dept. of Cardiology and Neurology, College of Korean medicine, Kyung-Hee University

Correspondence to: Seungwon Kwon, KyungHeeDaeRo 23, KyungHee University Korean Medicine Hospital, Dongdaemun-Gu, Tel : +82-2-958-9190, Fax : +82-2-958-9132, E-mail : kkokkottung@hanmail.net

Received 2022 July 20; Revised 2022 August 9; Accepted 2022 August 16.

Abstract

Objectives

This study was designed to investigate the clinical effectiveness of Ikgibohyeol-tang(Yìqìbǔxuè-tāng) granules and Deer antler granules on fatigue symptoms.

Methods

This is a 39-patient case series from a retrospective chart review of outpatients who were treated with Ikgibohyeol-tang granules and Deer antler granules at a Kyung Hee University Korean Medicine Hospital (Seoul) between 1st, January 2015 to 1st, August 2021. We reviewed the patients who complained of fatigue and analyzed changes in the degree of discomfort with fatigue and accompanying symptoms and HRV (Heart Rate Variability) score before and after treatment.

Results

After taking Ikgibohyeol-tang granules and Deer antler granules, the degree of discomfort with fatigue and accompanying symptoms decreased significantly compared to before taking them. After treatment, Autonomic nervous system activity, Stress resistance, Heart Stability increased, and Stress index, Degree of fatigue decreased significantly.

Conclusions

This study showed subjective symptoms and objective indicator (HRV score) were improved by taking Ikgibohyeol-tang granules and Deer antler granules.

Keywords: Ikgibohyeol-tang; Deer antler; Fatigue; HRV

Fig. 1

The remaining degree of discomfort with fatigue and accompanying symptoms after treatment.

Fig. 2

Comparison of differences in HRV scores before and after IGBHT granules and Deer antler granules administration (*p<.05, **p<.01, ***p<.001). HRV, Heart Rate Variability; ANS, Autonomic nervous system

Table 1

Composition of IGBHT granules per pack

Table 2

Composition of Deer antler granules per pack

Table 3

Past medical history of patients

Table 4

Main impression of patients

Table 5

Chief complaint of patients accompanied with fatigue

Table 6

Change of HRV scores after IGBHT granules and Deer antler granules administration

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