The Effect of Geopungchunghyul-dan on Circumferential Strain of Carotid Artery: A Case Series

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J Korean Med. 2018;39(1):86-94

Publication date (electronic) : 2018 March 31

doi : https://doi.org/10.13048/jkm.18009

Sang-Kwan Moon ¹^,², Minho Jung ¹, Seungwon Kwon ¹^,², Seung-Yeon Cho ¹^,², Seong-Uk Park ¹^,², Woo-Sang Jung ¹^,², Jung-Mi Park ¹^,², Chang-Nam Ko ¹^,², Ki-Ho Cho ¹^,²

¹Department of Cardiology and Neurology, Kyung Hee University Korean Medicine Hospital

²Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University

Correspondence to: 정민호 (Minho Jung), 경희대학교 한의과대학 순환신경내과학 교실, Tel: +82-2-958-9129, Fax: +82-2-958-9104, E-mail: tox37@naver.com

Received 2017 November 30; Revised 2018 March 5; Accepted 2018 March 2.

Abstract

Objectives

This study is aimed to examine the effect of Geopungchunghyul-dan on circumferential strain of carotid artery in outpatients of Kyung Hee University hospital of Korean Medicine.

Methods

Retrospective chart review is used from June 2016 to August 2017 for outpatients of Kyung Hee University hospital of Korean Medicine. 14 patients taking Geopungchunghyul-dan over 1 month were speculated. Data of circumferential strain and intima-media thickness was taken from carotid ultrasonography and processed by Wilcoxon signed-rank test.

Results

Geopungchunghyul-dan lowered circumferential strain of both carotid arteries after 1 month of administration (p<0.05). Intima-media thickness of both carotid arteries did not changed significantly.

Conclusions

Geopungchunghyul-dan may ameliorate arterial stiffness.

Keywords: Geopungchunghyul-dan; Circumferential strain; Arterial stiffness

Fig. 1

Change of left circumferential strain for 1 month of treatment.

Fig. 2

Change of right circumferential strain for 1 month of treatment.

Fig. 3

Change of left circumferential strain for 2 months of treatment

Fig. 4

Change of right circumferential strain for 2 months of treatment

Fig. 5

Change of both circumferential strain for 3 months of treatment

Table 1

Clinical Characteristics of Patients. (n=14)

Table 2

Mean Value and Standard Deviation of Circumferential Strain and Intima-Media Thickness of each Common Carotid Artery at Start(Baseline) and 1 Month of Treatment.

Table 3

Rate of Change in Circumferential Strain for 1 Month of Treatment

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