Review of Korean Medicine Treatments for Behcet’s Disease in Korean Journals

Ju-Hyun Lee; Jeong-Moon Lee; Keol Sohn; Lee, Ju-Hyun; Lee, Jeong-Moon; Sohn, Keol

doi:10.13048/jkm.25049

JKM > Volume 46(3); 2025 > Article

Lee, Lee, and Sohn: Review of Korean Medicine Treatments for Behcet’s Disease in Korean Journals

Review Article

The Journal of Korean Medicine 2025; 46(3): 283-297.

Published online: September 1, 2025

DOI: https://doi.org/10.13048/jkm.25049

Review of Korean Medicine Treatments for Behcet’s Disease in Korean Journals

Ju-Hyun Lee¹^{, *}

, Jeong-Moon Lee²

, Keol Sohn²

¹Department of Medical Support, Imsil-gun Medical Center

²Department of Korean Medicine, Graduate School of Wonkwang University

Correspondence to: Ju-Hyun Lee, Department of Medical Support, Imsil-gun Medical Center, 1680 Hoguk-ro, Imsil, 55927, Jeollabuk-do, Republic of Korea, Tel: +82-63-640-3338, Fax: +82-63-640-3317, E-mail: tony9403@naver.com

Received July 15, 2025 Revised August 6, 2025 Accepted August 12, 2025

Abstract

Objectives

This study aims to collect and analyze the clinical researches of Korean medicine treatment for behcet’s disease, and to provide basis for additional research and treatment of behcet’s disease.

Methods

Three researchers used six search engines to search for papers on Korean medicine treatment for behcet’s disease published from January 1, 2000 to December 31, 2024. Bibliographic information, main and accompanied symptoms, treatment period, treatment method (Herbal Medicine and Acupuncture), assessment scale, and outcome after treatment of 11 retrieved articles were analyzed.

Results

The most common symptom of behcet’s disease was pain (11 times). The most frequently used herbs were Dioscorea polystachya (18 times), Atractylodes macrocephala (17 times), Poria cocos (17 times), Bupleurum falcatum (16 times), and Crataegus pinnatifida (15 times), which were the composition of commonly used herbal medicine, Cheongyeoljeseub-bang (12 times), Chunsimyonnja-tang Gami (3 times), Chunsimyonnja-tang (2 times), Yangkyuk-san Gami (2 times), and Bojungikgi-tang Gami (2 times). The commonly used meridians were the Gall Bladder (17 times), Stomach (8 times), Large Intestine (7 times), and Spleen (6 times). The frequently mentioned acupoints were GB39 (3 times), LI11 (3 times), and Ashi point (3 times).

Conclusions

Based on the above data, more reasonable research and treatment for behcet’s disease can be made in the future.

Keywords: Systematic Review, Traditional Medicine, Behcet’s Disease, Herbal Medicine, Acupuncture

Fig. 1

Selection of Studies for Inclusion in the Review

Table 1

List of Selected Studies

Author (Year)	Title	Journal
Ahn et al. (2002)8)	A Case of Behcet’s Syndrome	The Journal of Korean Oriental Chronic Disease
Yang et al. (2009)9)	A Case of Suggested Behcet’s Disease Patient Treated by Gamchosasim-tang	The Journal of Korean Medicine Obstetrics & Gynecology
Jeong et al. (2018)10)	A Case of Korean Medicine for Abdominal Pain due to Behcet’s Disease	The Journal of Jeahan Oriental Medical Academy
Min et al. (2022)11)	Traditional Korean Medicine for Treating Beçhet’s Disease Symptoms of the Upper Burner: A Case Report	The Journal of Internal Korean Medicine
Lee et al. (2002)12)	A Clinical Review of Oral Ulcerations Induced Behçet’s Disease	The Journal of Internal Korean Medicine
Kim et al. (2007)13)	A Case Study of One Patient Who Has Central Dizziness and Ataxia Caused by Neuro-Behcet’s Diseases	Journal of Korean Medicine Rehabilitation
Lee et al. (2013)14)	Effect of Needle-Embedding & Acupuncture Therapy on Shoulder Pain in Behcet Disease Patient: A Case Report	Journal of Acupuncture Research
Baek et al. (2012)15)	A Case of Erythema Nodosum-Like Lesions of a Behcet’s Disease Patient Treated with Wolbi-Tang	The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Kang et al. (2021)16)	A Case of Xerostomia that Occurred during Behcet’s Disease Drug Treatment of a Person with Physical Disability	The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
Lim & Park (2014)17)	Two Cases Reports of Behcet’s Disease with Arthritis Treated with Oriental Medical Treatment Including Cheongsimyeonja-tang and Cheonglijagam-tang on Each	Korean Journal of Physiology & Pathology
Kim et al. (2000)18)	A Case Report of Neuro-Behcet’s Disease with Paraparesis	Journal of Korean Medicine

Table 2

Accompanied Disease Type

Disease	Frequency
Neuro Behcet’s Disease	2
Sweet Syndrome	1
Xerostomia (Drug Induced)	1

Table 3

Main and Accompanied Symptoms

	Symptom	Frequency
Main Symptom	Pain	11
Main Symptom	Ulcer	9

Accompanied Symptoms	Fatigue	4
	Visual Disturbance	3
	Hot Flush (Afternoon)	2
	Insomnia (Sleeping Disorder)	2
	Fever	2
	Dizziness	2
	Sweating	2
	Joint Stiffness	2
	Thirst	1
	Asthenopia	1
	Erythema	1
	Nodule	1
	Tenderness	1
	Edema	1
	Sensation of Heat	1
	Pruritus	1
	Papule	1
	Headache	1
	Tremor	1
	Skin Rash	1
	Abdominal Pain	1
	Diarrhea	1
	Dyspepsia	1
	Gingival Bleeding	1
	Quadriplegia	1
	Dysphasia (Mild)	1
	Xerostomia	1
	Skin Lesion	1
	Scar	1
	Gait Ataxia	1
	Paresthesia	1
	Heaviness of the Body	1
	Limitation of Motion	1
	Anorexia	1
	Abdominal Bloating	1
	Brain Fog	1
	Palpitation	1

Table 4

Prescriptions and Herbs

	Name	Frequency
Prescriptions	Cheongyeoljeseub-bang	12
	Chunsimyonnja-tang Gami	3
	Chunsimyonnja-tang, Yangkyuk-san Gami, Bojungikgi-tang Gami	2
	Cheongyeolyijin-tang Hab Yongdamsagan-tang Gami, Gamchosasim-tang, Gagampyungwee-san, Sodo-hwan, Soyangin Hyeungbangjihwang-tang, Soyangin Hyeongbangdojeok-san, Wolbi-tang, Chonglijagam-tang Gami, Sosiho-tang, Gihwangbeakho-tang, Oncheong-eum, Shoulder Pain A	1
Herbs	Dioscorea japonica Thunb. (山藥)	18
	Atractylodes japonica Koidz. ex Kitam. (白朮), Poria cocos (Schw.) Wolf (茯苓)	17
	Bupleurum falcatum L. (柴胡)	16
	Crataegus pinnatifida Bunge (山楂)	15
	Plantago asiatica L. (車前子), Alisma orientale (Sam.) Juz. (澤瀉)	14
	Nelumbo nucifera Gaertn. (蓮子肉), Scutellaria baicalensis Georgi (黃芩) Gardenia jasminoides J.Ellis (梔子)	13
	Geoclemys reevesii Gray. (龜甲), Dendrobium nobile Lindl. (石斛) Phyllostachys nigra var. henonis Stapf. (竹葉), Coix lacryma-jobi L. var. ma-yuen (Rom.Caill.) Stapf (薏苡仁) Fritillaria ussuriensis Maxim. (貝母), Glycyrrhiza uralensis Fisch. (甘草)	12
	Lonicera japonica Thunb. (金銀花), Aralia continentalis Kitag. (獨活) Fagopyrum esculentum Moench (蕎麥), Scrophularia buergeriana Miq. (玄蔘) Ostrea gigas Thunb. (牡蠣)	10
	Houttuynia cordata Thunb. (魚腥草)	8
	Chrysanthemum indicum (甘菊), Curcuma longa L. (薑黃) Liriope platyphylla F.T.Wang & T.Tang (麥門冬), Coptis japonica (Thunb.) Makino (黃連)	7
	Achyranthes japonica (Miq.) Nakai (牛膝), Angelica gigas Nakai (當歸) Dimocarpus longan Lour. (龍眼肉) Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H.F.Chow (酸棗仁) Asparagus cochinchinensis (Lour.) Merr. (天門冬), Corydalis ternata Nakai (玄胡索) Rehmannia glutinosa (Gaertn.) DC. (生地黃)	6
	Raphanus sativus Linné (蘿菔子), Chaenomeles sinensis (Thouin) Koehne (木瓜) Thuja orientalis L. (柏子仁), Acorus gramineus Sol. (石菖蒲), Polygala tenuifolia Willd. (遠志) Pueraria lobata (Willd.) Ohwi (葛根), Citrus unshiu Markovich (陳皮) Fossilia Ossis Mastodi (龍骨)	5
	Ligusticum tenuissimum (Nakai) Kitag. (藁本), Ulmus davidiana var. japonica (柳根皮) Angelica dahurica (Fisch. ex Hoffm.) Benth. & Hook.f. ex Franch. & Sav. (白芷) Amomum villosum Lour. (砂仁), Ziziphus jujuba Mill. (大棗), Cnidium officinale Makino (川芎) Panax ginseng C.A.Mey. (人蔘), Fallopia japonica (Houtt.) Ronse (虎杖根)	4
	Ostericum koreanum (Maxim.) Kitag. (羌活), Zingiber officinale Roscoe (乾薑) Salvia miltiorrhiza Bunge (丹參), Gypsum Fibrosum (石膏) Rehmannia glutinosa (Gaertn.) DC. (熟地黃), Cimicifuga heracleifolia Kom. (升麻) Massa Medicata Fermentata (神麴), Boswellia carterii Birdw. (乳香) Schizonepeta tenuifolia (Benth.) Briq. (荊芥), Astragalus membranaceus (Fisch.) Bunge (黃芪) Phellodendron amurense Rupr. (黃柏), Paeonia lactiflora Pall. (芍藥) Pinellia ternata (Thunb.) Makino (半夏)	3
	Psoralea corylifolia L. (破古紙), Vitex rotundifolia L.f. (蔓荊子) Paeonia suffruticosa Andrews (牡丹皮), Akebia quinata (Houtt.) Decne. (木通) Aucklandia lappa Decne. (木香), Commiphora myrrha (Nees) Engl. (沒藥) Saposhnikovia divaricata (Turcz.) Schischk. (防風), Sophora tonkinensis Gapnep. (山豆根) Cornus officinalis Siebold & Zucc. (山茱萸), Panax notoginsengs (Burk) F. H. Chen (三七根) Zingiber officinale Roscoe (生薑), Ligustrum lucidum Ait (女貞子) Forsythia viridissima Lindl. (連翹), Rhois Galla (五倍子), Clematis mandshurica Rupr. (威靈仙) Lithospermum erythrorhizon Siebold & Zucc. (紫草) Phyllostachys nigra (Lodd.) Munro var. henonis (Mitford) Stapf ex Rendle (竹茹) Cyperus rotundus L. (香附子), Magnolia officinalis Rehder & E.H.Wilson (厚朴) Agastache rugosa (Fisch. & C.A.Mey.) Kuntze (藿香)	2
	Terminalia chebula Retz. (訶子), Rehmannia glutinosa (Gaertner) Liboschitz (乾地黃) Gallus gallus domesticus Brisson (鷄內金), Trichosanthes kirilowii Maximowicz (栝樓子) Citrus reticulata Blanco (橘皮), Platycodon grandiflorus (Jacq.) A.DC. (桔梗) Areca catechu L. (大腹皮), Alpinia officinarum Hance (良薑), Borneolum (龍腦) Ephedra sinica Stapf (麻黃), Amomum kravanh Pierre ex Gagnep. (白豆蔻) Dictamnus dasycarpus Turcz. (白鮮皮), Hedyotis diffusa Willd. (白花蛇舌草) Curcuma zedoaria (Berg.) Rosc. (蓬朮), Sparganium stoloniferum Buch.-Ham. ex Graebn. (三稜) Cryptotympana pustulata Fabricius (蟬蛻), Perilla frutescens var. crispa (Thunb.) Deane (蘇葉) Dipsacus asperoides C.Y.Cheng & T.M.Ai (續斷) Trogopterus xanthipes (Milne Edwards) (五靈脂), Lindera aggregata (Sims) Kosterm. (烏藥) Zea mays L. (玉髮), Ulmus pumila Linné (楡白皮), Peucedanum praeruptorum Dunn (前胡) Syzygium aromaticum (L.) Merr. & L.M.Perry (丁香), Ailanthus altissima for. altissima (樗根白皮), Rheum palmatum L. (大黃) Kochia scoparia Schrader (地膚子), Poncirus trifoliata Rafin. (枳實) Sanguisorba officinalis L. (地楡), Anemarrhena asphodeloides Bunge (知母) Atractylodes lancea (Thunb.) DC. (蒼朮), Thuja orientalis L. (側柏葉) Zanthoxylum piperitum (L.) DC. (川椒), Amomum tsao-ko Crevost & Lemarié (草果) Gentiana scabra Bunge (草龍膽), Piper longum Linné (蓽撥), Eclipta prostrata (L.) L. (旱蓮草) Piper nigrum L. (胡椒), Betula platyphylla Suk. (樺皮)	1

Table 5

Meridians and Acupoints

		Frequency
Acupoints	GB39 (懸鐘), LI11 (曲池), Ashi Point 3
	LR01 (大敦), SP01 (隱白), ST36 (足三里), GB21 (肩井), GB31 (風市), GB34 (陽陵泉), GB40 (坵墟), GB41 (足臨泣), LI10 (手三里)	2
	SI05 (陽谷), HT08 (少府), SP02 (大都), SP04 (公孫), SP05 (商丘), ST37 (上巨虛), LU08 (經渠), PC06 (內關), CV12 (中脘), ST21 (梁門), EX-HN12 (金津), EX-HN13 (玉液), HT07 (神門), LU05 (尺澤), GV20 (百會), GB07 (曲鬢), GB20 (風池), GB30 (環跳), GB29 (居髎), HT03 (少海), SI08 (小海), BL36 (承扶), BL40 (委中), ST31 (髀關), ST32 (伏兎), ST33 (陰市), BL62 (神脈), KI06 (照海), BL60 (崑崙), ST41 (解谿), SP06 (三陰交), PC07 (大陵), LI04 (合谷), SI02 (前谷), SI03 (後谿), TE05 (外關), TE02 (液門), TE06 (支溝), LI05 (陽谿), Stomach Jeonggyeok, Lung Seunggyeok	1
Meridians	Gall Bladder	17
	Stomach	8
	Large Intestine	7
	Spleen	6
	Small Intestine, Bladder	4
	Triple Energizer, Heart	3
	Liver, Pericardium, Lung	2
	Kidney, Conception Vessel, Governor Vessel	1

Table 6

Summary of Case Reports

Author (Year)	Subject (Sex/Age)	Treatment Period (Days)	Acupuncture	Herbal Medicine	Result
Ahn et al. (2002)	F/38	29	-	Cheongyeolyijin-tang Hab Yongdamsagan-tang Gami	Ulcer Improved Pain Improved Fatigue Improved
Yang et al. (2009)	F/45	11	-	Gamchosasim-tang	Ulcer Improved Pain Improved Asthenopia Improved Skin Lesion Diameter Reduced Skin Lesion Border, Color Faded
Jeong et al. (2018)	F/59	6	HT08, SP02, LR01, SP01	Gagampyungwee-san	Diarrhea Improved Abdominal Pain Improved (100 → 15%) Dizziness Improved Fatigue Improved Dyspepsia Improved
Min et al. (2022)	M/42	22	SP01, SP04, SP05, ST36, ST37, LR01, LU08, PC06	Cheongyeoljeseub-bang 1–12 Hwangryunhaedok-tang (EX) Shihogayonggolmoryo-tang (EX) Yeonkyopaedok-san (EX) Sodo-hwan	Cervical Pain NRS 4 → 1 Ophthalmalgia NRS 5 → 1 Thirst Grade 8 → 1 Right Wrist Pain NRS 7 → 1
Lee et al. (2002)	M/42	15	-	Yangkyuk-san Gami 1 Yangkyuk-san Gami 2 Yongseog-san (Ex)	Symptoms Not Improved
	M/46	47	Stomach Jeonggyeok, CV12, ST21, EX-HN12, EX-HN13, HT03, HT07, LU05	Bojungikgi-tang Gami 1 Bojungikgi-tang Gami 2 Yongseog-san (Ex)	Ulcer Improved Pain Improved
Kim et al. (2007)	M/47	25	GV20, GB07, GB21, GB31, ST36, GB39, LI11	Soyangin Hyeungbangjihwang-tang Soyangin Hyeongbangdojeok-san	Dizziness VAS 10 → 1 Gait Ataxia Grade 7 → 0
Lee et al. (2013)	M/51	32	LI11, LI10, SI05, SI02, SI03, TE05, TE02, TE06	Shoulder Pain A	Shoulder Pain VAS 10 → 4 Shoulder ROM Increased
Baek et al. (2012)	F/28	11	Lung Seunggyeok	Wolbi-tang	Erythema Improved Edema Improved Sensation of Heat Improved Pain Improved Ulcer Not Improved Pruritus Improved
Kang et al. (2021)	F/60	179	GB20, GB21	Palmul-tang (EX)	YDQ, OHIP-14, XI, VAS (Oral Pain) Improved VAS (Cervical & Shoulder Pain), SPADI, EQ-VAS Improved
	F/46	26	GB30, GB29, GB31, GB34, GB39, GB40, GB41, BL36, BL40, ST31, ST32, ST33, Ashi Point	Chunsimyonnja-tang Chunsimyonnja-tang Gami	Joint Pain VAS 10 → 3 Ulcer VAS 10 → 5 Hot Flush (Afternoon) VAS 10 → 4–5 Sweating VAS 10 → 4–5 Sleep Time Increased Sleep Quality Improved
Lim & Park (2014)	F/44	68	GB40, BL62, KI06, BL60, ST41, GB41, GB39, GB34, SP06, LI05, LI11, LI10, SI08, PC07, LI04, Ashi Point	Chunsimyonnja-tang Chunsimyonnja-tang Gami 1 Chunsimyonnja-tang Gami 2 Chonglijagam-tang Gami	Joint Pain VAS 10 → 4–5 Heaviness of the Body VAS 10 → 6 Joint Stiffness VAS 10 → 6 Hot Flush (Afternoon) VAS 10 → 6 Sweating VAS 10 → 6 Sleep Time Increased Sleep Quality Improved
Kim et al. (2000)	F/40	24	Ashi Point	Sosiho-tang Gihwangbeakho-tang Oncheong-eum Yeonkyopaedok-san (EX)	Pain Improved Ulcer Improved Quadriplegia Not Improved Tremor Not Improved Fever Improved

* EQ-VAS: European Quality of Life Visual Analogue Scale; NRS: Numeric Rating Scale; OHIP-14: Oral Health Impact Profile-14; ROM: Range of Motion; SPADI: Shoulder Pain and Disability Index; VAS: Visual Analogue Scale; XI: Xerostomia Inventory; YDQ: Yin-Deficiency Questionnaire

참고문헌

1. Sung, Y. K. (2013). Treatment of behcet disease. J Korean Ophthalmol Soc, 41(10), https://doi.org/10.3904/kjm.2013.84.2.196

2. Park, J. W., Koh, H. J., & Kim, H. B. (2002). Behcet’s disease in Korean. J Korean Ophthalmol Soc, 43(1), 67-74.

3. Saleh, Z., & Arayssi, T. (2014). Update on the therapy of behçet disease. Ther Adv Chronic Dis, 5(3), 112-134. https://doi.org/10.1177/2040622314523062

4. Mendoza-Pinto, C., Garcia-Carrasco, M. G., Jiménez-Hernández, M., Hernández, C. J., Ribeling-Navarro, C., & Zavala, A. N., et al (2010). Etiopathogenesis of behcet’s disease. Autoimmun Rev, 9(4), 241-245. https://doi.org/10.1016/j.autrev.2009.10.005

5. Kim, H. J., & Chae, B. Y. (1999). Clinical observation of behset’s disease patients by oriental medicine. J Korean Med Ophthalmol Otolaryngol Dermatol, 12(1), 387-395.

6. Kang, N. R., Han, J. M., Ko, W. S., & Yoon, H. J. (2012). A study on the skin disease of Sanghanron and Geumgweyoryak. J Korean Med Ophthalmol Otolaryngol Dermatol, 25(1), 55-74. https://doi.org/10.6114/jkood.2012.25.1.055

7. Yong, S., Gu, H., Kim, D., Sohn, K., & Yun, Y. (2014). Analysis of clinical researches on traditional medicine treatment for behcet’s disease in Korea, China, and Japan. The Society of Korean Preventive Medicine, 18(1), 67-82.

8. Ahn, C. J., Park, C. S., & Choi, S. Y. (2002). A case of behcet’s syndrome. J of Oriental Chr Dis, 8(1), 92-98.

9. Yang, D. S., Gu, H. J., Yang, S. J., Jo, S. H., & Park, K. M., et al (2009). A case of suggested behcet’s disease patient treated by Gamchosasim-tang. J Korean OBstet Gynecol, 22(4), 188-194.

10. Jeong, Y. E., Kim, J. D., & Kang, S. B. (2018). A case of Korean medicine for abdominal pain due to behcet’s disease. The Journal of Jehan Oriental Medical Academy, 16(1), 1-8.

11. Min, S., Moon, J., Kim, Y., Park, J., Hong, J., & Jeong, J. C. (2022). Traditional Korean medicine for treating beçhet’s disease symptoms of the upper burner: A case report. Korean J Intern Med, 43(2), 130-143. https://doi.org/10.22246/jikm.2022.43.2.130

12. Lee, J. Y., Baek, D. G., Cho, G. W., Choi, W. J., Jung, D. Y., & Shin, S. H., et al (2002). A clinical review of oral ulcerations induced behçet’s disease. Korean J Intern Med, 23(3), 479-485.

13. Kim, K. H., Kim, S. J., Park, C. K., Woo, I., & Jeong, S. M. (2007). A case study of one patient who has central dizziness and ataxia caused by neuro-behcet’s diseases. J Korean Med Rehabi, 17(3), 207-216.

14. Lee, S. M., Ji, Y. S., Jeon, J. H., Kim, J. H., & Kim, Y. I. (2013). Effect of needle-embedding & acupuncture therapy on shoulder pain in behcet disease patient: A case report. J Acupunct Res, 30(4), 219-224. https://doi.org/10.13045/acupunct.2013040

15. Baek, S. C., Jo, S. H., Jo, E. H., & Park, M. C. (2012). A case of erythema nodosum-like lesions of a behcet’s disease patient treated with Wolbi-Tang. J Korean Med Ophthalmol Otolaryngol Dermatol, 25(2), 83-91. https://doi.org/10.6114/jkood.2012.25.2.083

16. Kang, B. S., Kang, D., & Kim, J. H. (2021). A case of xerostomia that occurred during behcet’s disease drug treatment of a person with physical disability. J Korean Med Ophthalmol Otolaryngol Dermatol, 34(1), 112-135. https://doi.org/10.6114/jkood.2021.34.1.112

17. Lim, T. H., & Park, H. S. (2014). Two cases reports of behcet’s disease with arthritis treated with oriental medical treatment including Cheongsimyeonja-tang and Cheonglijagam-tang on each. J Physiol & Pathol Korean Med, 28(6), 643-649.

18. Kim, H. J., Lee, J. L., & Shin, H. D. (2000). A case report of neuro-behcet’s disease with paraparesis. J Korean Med, 21(4), 286-291.

19. Davatchi, F. (2012). Diagnosis/classification criteria for behcet’s disease. Patholog Res Int, (2012). (1), 607921. https://doi.org/10.1155/2012/607921

20. Lee, S. G., & Ahn, K. S. (2004). Experimental studies on the kinds of Sasim-tang in behçet’s disease symptoms in ICR mice. J Physiol & Pathol Korean Med, 18(4), 1061-1070.

21. Lim, H. J., Hwang, C. Y., Chiang, H. C., Kim, N. K., & Kwon, I. H. (2002). Inhibitory effects of Onchungeum on cytokine production from phytohaemagglutinin-stimulated peripheral blood mononuclear cells of behcets patients. J Physiol & Pathol Korean Med, 16(4), 768-773.

22. Min, S., Moon, J., Kim, Y., Park, J., Hong, J., & Jeong, J. C. (2022). Traditional Korean medicine for treating beçhet’s disease symptoms of the Upper Burner: A case Report. J Int Korean Med, 43(2), 130-143. https://doi.org/10.22246/jikm.2022.43.2.130

23. Kwon, Y. C., & Bae, H. S. (1985). A literary review on Cheongsimyeonja-eum applied to stroke treatment. J Korean Med, 6(1), 55-59.

24. Jea, H. K., Ahn, J. H., Hwang, M. L., Kim, S. Y., & Jung, H. A. (2019). Three cases of nummular eczema patients treated with Cheongshimyeonja-eum Gagambang and Soyeom pharmacopuncture. J Korean Med Ophthalmol Otolaryngol Dermatol, 32(2), 107-119. https://doi.org/10.6114/jkood.2019.32.2.107

25. Ko, S. J., Shin, Y. J., Jang, W. S., Ha, Y. J., Lee, S. A., & Ahn, M. S. (2013). Protective effects of Chungsimyeonja-eum on glutamate -induced apoptosis in C6 glial cells. J Int Korean Med, 31(1), 54-65.

26. Kim, S. H., Lee, J. Y., & Lee, K. S. (2017). A case study on Yanggyeokssan for pediatric patient with chronic ankle sprain. Journal of the Korean Society of Morphology, 18(1), 443-457.

27. Lee, Y. S., Han, J. K., & Kim, Y. H. (2012). Anti-allergic effects of Gagam-YangGyeokSan on RBL-2H3 mast cells and OVA/alum sensitized mice. J Korean Orient Pediatric, 26(4), 10-23. http://dx.doi.org/10.7778/jpkm.2012.26.4.010

28. Deng Z.(2019). Deng Zhongjia Herbal Formula Lecture. 1st ed. Paju. Mulgogisup;p. 484-490.

29. Ju Y. S.(2013). Jeungbo Ungok Herbology. Wanju. Wooseok.

30. National College of Korean Medicine and Graduate Schools of Korean Medicine Meridian and Acupoint Textbook Compilation Committee. (2020). Acupuncture Points 2. Seoul. Jeongdam;p. 230-237. p. 364-368.

31. National College of Korean Medicine and Graduate Schools of Korean Medicine Meridian and Acupoint Textbook Compilation Committee. (2020). Acupuncture Points 1. Seoul. Jeongdam;p. 52-56. p. 93-98. p. 126-132. p. 288-292.