A Case Report of Hypersensitivity Vasculitis with Petechiae Improved by Administration of Jeoryoung-tang

Ju-Hyun Lee; Eun-Heui Jo; Ji-Won Park; Min-Cheol Park; Lee, Ju-Hyun; Jo, Eun-Heui; Park, Ji-Won; Park, Min-Cheol

doi:10.13048/jkm.22024

JKM > Volume 43(2); 2022 > Article

Lee, Jo, Park, and Park: A Case Report of Hypersensitivity Vasculitis with Petechiae Improved by Administration of Jeoryoung-tang

Case Report

The Journal of Korean Medicine 2022; 43(2): 117-123.

Published online: June 1, 2022

DOI: https://doi.org/10.13048/jkm.22024

A Case Report of Hypersensitivity Vasculitis with Petechiae Improved by Administration of Jeoryoung-tang

Ju-Hyun Lee¹

, Eun-Heui Jo²^{, 3}

, Ji-Won Park²

, Min-Cheol Park¹^{, 3}^{, *}

¹Department of Ophthalmology, Otolaryngology & Dermatology, College of Korean Medicine, Wonkwang University

²Department of Korean Medicine Acupuncture and Moxibustion, College of Korean Medicine, Wonkwang University

³Research Center of Traditional Korean Medicine, Wonkwang University

Correspondence to: Min-Cheol Park, Department of Ophthalmology, Otolaryngology and Dermatology, Wonkwang University Korean Medicine Hospital 895 Muwang-ro, Iksan-si, Jeollabuk-do, 54538, Republic of Korea, Tel: +82-63-859-2821, Fax: +82-63-841-0033, E-mail: spinx11@wonkwang.ac.kr

Received March 22, 2022 Revised May 13, 2022 Accepted May 23, 2022

Abstract

Objectives

This study is to report a case of hypersensitivity vasculitis with petechiae improved by Jeoryoung-tang

Methods

Petechiae was observed in the upper and lower extremities of the patient. The patient also complained of cystitis symptoms such as dysuria and residual urine. Since there were no other accompanying symptoms such as abdominal pain, bleeding, or joint pain, the patient was diagnosed with hypersensitivity vasculitis and Jeoryoung-tang was prescribed for about a month.

Results

After administering Jeoryoung-tang for about a month, petechiae improved from 8 to 2 points, and cystitis symptoms also improved from NRS 7 to 2 points.

Conclusions

Since it has been confirmed that Jeoryoung-tang was effective as the treatment of skin symptoms through this case, Jeoryoung-tang can be prescribed for patients with other type skin diseases. However, since it is difficult to generalize this single case, continuous follow-up studies should be conducted.

Keywords: Hypersensitivity Vasculitis, Cystitis, Jeoryoung-tang

Fig. 1

Treatment Timeline

Fig. 2

Clinical Progress of Petechiae

Table 1

Prescription of Jeoryoung-tang

	Name of Natural Medicine (Herbal Medicine)	Weight(g)
豬苓	Polyporus umbellatus FR.	6
白茯苓	Wolfiporia extensa	6
滑石	Talc	6
澤瀉	Alisma canaliculatum A.Braun & C.D.Bouché	6
阿膠	Donkey Hide Gelatin	6

Total Amount		30

Table 2

Petechiae Symptom Evaluation Index

	Symptom Severity
Extent	0=Absence
Darkness	1=Mild
Darkness	2=Moderate
Thermalgia	3=Severe

Table 3

Cystitis Symptom Evaluation Index

	Symptom Severity
Dysuria	0 (None) ~ 10 (Severe)
Residual Urine	0 (None) ~ 10 (Severe)

Table 4

Symptom Evaluation Progress of Petechiae

	2020.05.25	2020.06.09	2020.11.27
Extent	3	1	0
Darkness	3	1	0
Thermalgia	2	0	0

Total	8	2	0

Table 5

Symptom Evaluation Progress of Cystitis

	2020.05.25	2020.06.09	2020.11.27
Dysuria	4	1	0
Residual Urine	3	1	0

Total	7	2	0

참고문헌

1. Kwon KY. (2008). Diagnosis and treatment of purpura. The Korean Journal of Medicine;75(2):169-72.

2. Traditional Korean Dermatology & Surgery Textbook Compilation Committee. 2007. Text of traditional Korean dermatology & surgery. 1st ed. Busan: Sunwoo;463-6.

3. Kim JS, Choi JH, Kim JH, Jeong MY, & Park SY. (2016). A case of allergic purpura treated with Korean medicine-two cases. Herb Formula Sci;24(1):63-70.

4. Kang DW, Park JG, Han CY, Kim KS, & Kim YB. (2019). Review of Korean medicine treatments for purpura and vasculitis in Korean journals. J Korean Med Ophthalmol Otolaryngol Dermatol;32(3):116-35.

5. Mang WJ. (1996). Sanghanron commentary. 1st ed. Iksan. Wonkwang University Press Office;p. 297-9.

6. Kim BM, & Jo HG. (2020). Adjuvant therapy efficacy of herbal medicine Zeo Lyung Tang (Zhu Ling Decoction) for primary glomerulonephritis: Systemic review and meta-analysis. J Int Korean Med;41(4):633-57.

7. Lee CR, Kim TH, Rhee JW, Na BJ, Kim EJ, & Lee SH, et al. (2003). Case studies on the patients with urinary tract infection after stroke treated with Oryeong-san Gamibang(Wuring-san Jiaweifang). J Int Korean Med;168-75.

8. Zufferey A, Kapur R, & Semple JW. (2017). Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP). J Clin Med;6(2):16

9. Choi KC. (2001). Idiopathic thrombocytopenic purpura. Journal of the Korean Pediatric Society;44(2):115-8.

10. Kwon JM, & Pak KY. (2018). Poor prognosis in idiopathic thrombocytopenic purpura-associated retinopathy. J Korean Ophthalmol Soc;59(4):384-7.

11. Tizard EJ. (1999). Henoch-Schönlein purpura. Arch Dis Child Educ Pract Ed;80380-3.

12. Moon YJ, Kim CH, Chu HM, Lee JY, Song BK, & Won JH. (2018). A case report of hypersensitivity vasculitis improved by Korean medicine treatment. J Int Korean Med;39(5):964-72.

13. Kim BNR, Park JM, & Chae JW. (2014). A case report of allergic purpura. J Pediatr Korean Med;28(4):108-17.