AbstractObjectivesThe aim of this study is to investigate the anti-inflammatory effects of Ojeok-san and compare the therapeutic effects according to its formation.
MethodsWe evaluated the anti-inflammatory effects of Ojeok-san using lipopolysaccharide (LPS) induced inflammatory animal model. Male SD rats were administered intra-orally with two different formulation types of Ojeok-san according to prescribed dosage. One hour later, to induce inflammatory responses, subsequent intra-peritoneal injection of LPS was conducted. After 5 hours later, serum TNF-α, IL-1β, IL-6 and PGE2 levels were measured by ELISA to assess the alteration of pro-inflammatory markers.
AcknowledgementThis work was supported by a grant from Pharmacological Standardization Project of Traditional Korean Medicine by Ministry of Health and welfare (MOHW) and JeollaNamdo, Republic of Korea.
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