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JKM > Volume 41(1); 2020 > Article
Lee, Lee, Hong, Yun, and Park: A Case Report of Chronic Prostatitis/Chronic Pelvic Pain Syndrome(CP/CPPS) treated with Gyejibokryeong-hwan

Abstract

Objectives

Chronic Prostatitis/Chronic Pelvic Pain Syndrome(CP/CPPS) is diagnosed on the basis of symptoms, principally pain or discomfort in the pelvic region. Pathophysiology and treatment of this disease has not been established. CP/CPPS’s main symptom appears to be an incurable pain and Collateral disease’s(絡病) symptoms also appear as incurable pain in general.
The purpose of this study is to report the clinical effects of Gyejibokryeong-hwan(桂枝茯苓丸) based on removing Stasis and freeing Collateral disease on CP/CPPS in which pain appears largely.

Methods

The patient was treated with Gyejibokryeong-hwan. National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) was used to assess treatment effect.

Results

NIH-CPSI and Pelvic pain decreased significantly after treatment.

Conclusions

Gyejibokryeong-hwan was effective in treating CP/CPPS. Especially, there was a clear effect on Pelvic pain among the symptoms.

Fig. 1
Subdomain Score of NIH-Chronic Prostatitis Symptom Index
jkm-41-1-117f1.gif
Table 1
Composition of Gyejibokryeong-hwan
Herbal Name Pharmacogniostic Name A single Dose(mg)
桂枝 Cinnamomi Ramulus 500.0
茯笭 Hoelen 500.0
牧丹皮 Moutan Root Bark 500.0
芍藥 Peony Root 500.0
桃仁 Peach Kernel 500.0
Table 2
NIH-Chronic Prostatitis Symptom Index
jkm-41-1-117t1.gif
Table 3
Symptom and Total Score of NIH-Chronic Prostatitis Symptom Index
2018.10.30 2018.11.06 2018.12.04 2019.01.17 2019.01.31 2019.02.26
Symptom score 19 12 10 7 14 5
Total Score 30 17 15 11 22 8
Table 4
Pain Score of NIH-Chronic Prostatitis Symptom Index
2018.10.30 2018.11.06 2018.12.04 2019.01.17 2019.01.31 2019.02.26
Pain Localization
Perineal(Q1a) 1 0 0 0 1 0
Testicular (Q1b) 0 0 0 0 0 0
Tip of penis(Q1c) 0 0 0 0 0 0
Pubic area(Q1d) 0 0 0 0 0 0
Pain Symptom
Dysuria(Q2a) 0 0 0 0 0 0
Ejaculatory pain (Q2b) 1 0 0 0 0 0
Pain Quality
Pain Frequency(Q3) 5 2 2 1 3 1
Pain severity(Q4) 6 4 2 2 5 3
Herbal Medicine 1 dose tid 1 dose tid 1 dose tid 1 dose tid 1 dose tid 1 dose tid
Conventional Medicine (NSAID and antibiotics) + + +

참고문헌

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