The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points : A Cross-over Study

Jung-Wan Kim; Jae-Hong Kim; Yun-Kyoung Yim; Kim, Jung-Wan; Kim, Jae-Hong; Yim, Yun-Kyoung

doi:10.13048/jkm.18005

JKM > Volume 39(1); 2018 > Article

Kim, Kim, and Yim: The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points: A Cross-over Study

Original Article

The Journal of Korean Medicine 2018; 39(1): 44-54.

Published online: March 31, 2018

DOI: https://doi.org/10.13048/jkm.18005

The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points: A Cross-over Study

Jung-Wan Kim¹

, Jae-Hong Kim¹

, Yun-Kyoung Yim¹^{, *}

¹Department of Meridian & Acupoints, College of Korean Medicine, Daejeon University

Correspondence to: 임윤경 (Yun-Kyoung Yim), Department of Meridian and Acupoints, College of Korean Medicine, Daejeon University 62, Daehak-ro, Dong-gu, Daejeon, 34520, Republic of Korea. Tel: +82-42-280-2610, Fax: +82-42-280-2641 E-mail: docwindy@dju.kr

Received February 23, 2018 Revised March 15, 2018 Accepted March 15, 2018

Abstract

Objectives

The objective of this study is to investigate the effects of drinking alcohol on bio-electrical potential at twelve source points.

Methods

Twenty healthy adults were assigned to alcohol and water groups by a random cross-over design. Bio-electrical potential at twelve source points were measured before and after drinking alcohol or water and the change of bio-electrical potential was analyzed and compared between the alcohol and the water groups.

Results

Bio-electrical potential at LI4, ST42, KI3, PC7, TE4, GB40, LR3 in the alcohol group was significantly increased compared to those in the water group.

Conclusions

Drinking alcohol increased bio-electrical potential at source points of LI, ST, KI, PC, TE, GB and LR in healthy human subjects.

Keywords: Bio-electrical potential, Source points, Drinking, Alcohol

Fig. 1

Experimental protocol

Fig. 2

Change of Blood Alcohol Concentration (BAC)

Fig. 3

Effects of Alcohol on Bio-electrical potential at Twelve Source Points

Bio-electrical potential was detected at twelve source points before and after drinking alcohol or water. The detected signal was amplified and saved in the connected computer. The changes of bio-electrical potential at each time point was calculated and compared between the alcohol group and the water group. The scales on the y-axes are digital values converted with 16-bit resolution. Data were expressed as mean (n=20).

Red full circle: Alcohol group

Blue empty circle: Water group

* P < 0.05 vs Water group

Table 1

General Characteristics of Subjects

	Mean ± SD
Age(year)	22.67 ± 2.24
Height(cm)	171.14 ± 6.62
Weight(kg)	68.66 ± 12.69
BMI(kg/m²)	23.33 ± 3.52
Body Temperature(°C)	36.08 ± 0.51
Systolic Blood Pressure(mmHg)	123.49 ± 14.07
Diastolic Blood Pressure(mmHg)	78.13 ± 11.52
Time after urination(h)	0.57 ± 1.01

Table 2

Comparison of Bio-electrical Potential Change between the Alcohol Group and the Water group at Twelve Source Points

Source Point	P value (Alcohol vs Water)
LU9	0.126
LI4	0.005^*
ST42	0.005^*
SP3	0.129
HT7	0.070
SI4	0.129
BL64	0.134
KI3	0.011^*
PC7	0.013^*
TE4	0.013^*
GB40	0.010^*
LR3	0.023^*

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