JKM > Volume 39(1); 2018 > Article
Kim, Kim, and Yim: The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points: A Cross-over Study



The objective of this study is to investigate the effects of drinking alcohol on bio-electrical potential at twelve source points.


Twenty healthy adults were assigned to alcohol and water groups by a random cross-over design. Bio-electrical potential at twelve source points were measured before and after drinking alcohol or water and the change of bio-electrical potential was analyzed and compared between the alcohol and the water groups.


Bio-electrical potential at LI4, ST42, KI3, PC7, TE4, GB40, LR3 in the alcohol group was significantly increased compared to those in the water group.


Drinking alcohol increased bio-electrical potential at source points of LI, ST, KI, PC, TE, GB and LR in healthy human subjects.

Fig. 1
Experimental protocol
Fig. 2
Change of Blood Alcohol Concentration (BAC)
Fig. 3
Effects of Alcohol on Bio-electrical potential at Twelve Source Points
Bio-electrical potential was detected at twelve source points before and after drinking alcohol or water. The detected signal was amplified and saved in the connected computer. The changes of bio-electrical potential at each time point was calculated and compared between the alcohol group and the water group. The scales on the y-axes are digital values converted with 16-bit resolution. Data were expressed as mean (n=20).
Red full circle: Alcohol group
Blue empty circle: Water group
* P < 0.05 vs Water group
Table 1
General Characteristics of Subjects
Mean ± SD
Age(year) 22.67 ± 2.24
Height(cm) 171.14 ± 6.62
Weight(kg) 68.66 ± 12.69
BMI(kg/m2) 23.33 ± 3.52
Body Temperature(°C) 36.08 ± 0.51
Systolic Blood Pressure(mmHg) 123.49 ± 14.07
Diastolic Blood Pressure(mmHg) 78.13 ± 11.52
Time after urination(h) 0.57 ± 1.01
Table 2
Comparison of Bio-electrical Potential Change between the Alcohol Group and the Water group at Twelve Source Points
Source Point P value (Alcohol vs Water)
LU9 0.126
LI4 0.005*
ST42 0.005*
SP3 0.129
HT7 0.070
SI4 0.129
BL64 0.134
KI3 0.011*
PC7 0.013*
TE4 0.013*
GB40 0.010*
LR3 0.023*


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