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JKM > Volume 36(3); 2015 > Article
Eul-Hwa, Tae-Keun, Su-Jung, Do-Yean, Seng-Yean, and Seong-Hun: The Case Study of Lactobacillus mixture culture fluid on Atopic dermatitis

Abstract

Objectives:

Recently lactic acid formulation was known as the adjuvant therapy on atopic dermatitis(AD) symptoms because of little side effects. In this study, it was studied that Lactobacillus mixed culture appliment was effective on not on AD symptoms.

Methods:

The case-photos 30–40 times of AD symptoms from case were observed with literatures. The case-photos were acquired with environmental AD dermatitis experience program which is conducted in SUNCHANG RESERCH INSTITUTE OF HEALTH AND LONGEVITY from 2014.01 to 2014.08. Experience applicants were limited the oral administration and chemical external administration.

Results:

Lactobacillus mixed culture appliment was effective because of the mitigation or disappearance of AD primary symptoms like pruritus, erythema, edema, effusion, dry skin, scaly, scab etc. AD symptom degree was dependent on lactobacillus mixed culture appliment times, and classified as Reaction Period (RAP), Reduction Period (RDP), Efection Period (EP), Reproduction Period (RPP) on a single mixed culture appliment time.
And AD symptoms which were appeared in RPP were classified as Rebound Period (RBP), Effection Period (EP), Subclinical Period (SCP).

Conclusions:

Lactobacillus mixed culture appliment is considered to be useful for AD symptoms and is estimated to be effective by different mechanism with oral administration or steroid ointment application. Lactobacillus mixed culture appliment is expected to induce a synergistic effects on AD symptom reliefs with the other oral administration.

Fig. 1.
The SCORAD index of 3 case with Lactobacillus mixture culture appliments
jkm-36-3-135f1.tif
Fig. 2.
The atopy dermatitis symptoms cycle after Lactobacillus mixture culture single appliment
RAP; reaction period, RDP; reduction period, EP; effection period, RPP; reproduction period
Symptom lever line made by hands to depend on observer.
jkm-36-3-135f2.tif
Fig. 3.
The atopy dermatitis symptoms expression degrees on RPP after Lactobacillus mixture culture appliments
RBP; rebound period, EP; effection period, SCP; subclinical period Symptom lever line made by hands to depend on pictures.
jkm-36-3-135f3.tif
Table 1.
Compositions of herbal mixture extracts
Ingredient Contents(%)
인삼(Ginseng) 13%
황기(Scutellaria baicalensis) 13%
감초(Licorice) 18%
흑축(Pharbitis seed) 13%
녹차(Camellia sinesis) 13%
노회(Aloe succotrina) 30%
Table 2.
1st cases in skin coating treatment with lactobacillus mixture culture fluid on atopic dermatitis in buttock
횟수
부위
0회 4회 25회

jkm-36-3-135i1.tif jkm-36-3-135i2.tif jkm-36-3-135i3.tif
Table 3.
2nd cases in skin coating treatment with lactobacillus mixture culture fluid on atopic dermatitis in ankle
횟수
부위
0회 17회 26회


jkm-36-3-135i4.tif jkm-36-3-135i5.tif jkm-36-3-135i6.tif
Table 4.
3rd cases in skin coating treatment with lactobasillus mixture culture fluid on atopic dermatitis in face
횟수
부위
0회 3회 32회


jkm-36-3-135i7.tif jkm-36-3-135i8.tif jkm-36-3-135i9.tif

참고문헌

1. Hwang EK. The Clinical Significance of Fungal Allergy in Patients with Atopic Dermatitis. Ajou: Department of Medical Sciences, The Graduate School, Ajou University;Paper of master degree.2012. p. 1–34.


2. Pucheu-Haston C, Jackson H, Olivry T, Dunston S, Hammerberg B. Epicutaneous sensitization with Dermatophagoides farinae induces generalized allergic dermatitis and elevated mite-specific immunoglobulin E levels in a canine model of atopic dermatitis. Clin Exp Allergy. 2008; 38:667–679.
crossref

3. Schäfer T, Heinrich J, Wjst M, Adam H, Ring J, Wichmann HE. Association between severity of atopic eczema and degree of sensitization to aeroallergens in schoolchildren. J Allergy Clin Immunol. 1999; 104:1280–1284.
crossref

4. David TJ, Wells FE, Sharpe TC, Gibbs AC. Low serum zinc in children with atopic eczema. Br J Dermatol. 1984; 111:597–601.
crossref

5. Searing DA, Leung DY. Vitamin D in atopic dermatitis, asthma and allergic diseases. Immunol Allergy Clin North Am. 2010; 30:397–409.
crossref

6. Leung DY, Bieber T. Atopic dermatitis. Lancet. 2003; 361:151–160.
crossref

7. Schults-Larsen F, Hanifin JM. Epidermiology of atopic dermatitis. Immunol Allergy Clin. North Am. 2002; 22:1–24.
crossref

8. Soma Y, Kashima M, Imaizumi A, Takahama H, Kawakami T, Mizoguchi M. Moisturizing effects of topical nicotinamide on atopic dry skin. Int J Dermatol. 2005; 44:197–202.
crossref

9. Park TM. Effect of The Herbal Medicine Treatment for Gastrointestinal Dysfuction in Children with Atopic Dermatitis. Pocheon: Major in Comlementary Alternative Medicine Graduate School of Complementary Alternative Medicine;paper of master degree.2008. p. 1–43.


10. Shim WH, Song CH, Park HJ, Kim HS, Chin HW, Kim SH, et al. Clinical Characteristics of Itch in Patients with Adult and Childhood Atopic Dermatitis. Korean J Dermatol. 2011; 49:4. 318–327.


11. Howlett S. Emotional dysfunction, child–family relationships and childhood atopic dermatitis. Br J Dermatol. 1999; 140:381–384.
crossref

12. Foolad N, Brezinski EA, Chase EP. Armstrong AW(2012) Effect of nutrient supplementation on atopic dermatitis in children. Arch Dermatol. 2012; 17:1–6.


13. Pessi T, Sutas Y, Hurme M, Iolauri E. Interleukin-10 generation in atopic children following oral Lactobacillus rhamnosus GG. Clin. Exp. Allergy. 2000; 30:1804–1808.
crossref

14. Choi MO, Kim BJ, Jo SK, Jung HK, Lee JT, Kim HY, et al. Anti-allergic activities of Castanea crenata inner shell extracts fermented by Lactobacillus bifermentans. Korean J Food Preserv. 2013; 20:4. 583–591.
crossref

15. Park HS, Lee HS, Uhm TB. Selection of microorganisms for probiotics and their characterization. J. Korean Soc. Food Sci. Nutr. 1998; 27:433–440.


16. Klliomaki M, Ouwehand A, Arvilommi H, Kero P, Isolauri E. Transforming growth factor beta in the breastmilk: A potential regulator of atopic disease at an early age. J. Allergy Clin. Immun. 1999; 104:1251–1257.
crossref

17. Lee IH, Lee SH, Lee IS, Park YK, Chung DK, Cho RW. Effects of Probiotic Extracts of Kimchi on Immune Function in NC/Nga Mice. KOREAN J. FOOD. 2008; 40:1. 82–87.


18. Isolauri E, Rautava S, Kalliomaki M, Kirjavainen P, Salminen S. Role of probiotics in food hypersensitivity. Curr Opin Allergy Clin Immunol. 2002; 2:263–71.
crossref

19. Van Der Aa LB, Heymans HSA, Van Aalderen WMC, Sprikkelman AB. Probiotics and prebiotics in atopic dermatitis: review of the theoretical background and clinical evidence. Pediatr Allergy Immunol. 2010; 21:355–67.
crossref

20. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995; 125:1401–12.


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