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JKM > Volume 36(1); 2015 > Article
Lee, Yang, and Chang: A Case Report on Two Psoriasis Patients with Insomnia



The purpose of this study is to present two treatment cases of psoriasis with insomnia.


We administered Guibi-tang medication to the psoriasis patients with insomnia and tested the results by Psoriasis Area and Severity Index (PASI) and Insomnia Severity Index (ISI) as well.


After the treatment both the patients showed improvements in PASI and ISI as well. PASI of Patient 1 changed from 15.2 to 1.2 along with the change of ISI from 27 to 2. In case of Patient 2, PASI changed from 14.6 to 1.8 while ISI changed from 21 to 6.


The results suggest that Guibi-tang can be an effective treatment for insomnia and psoriasis as well. Further studies will be needed to demonstrate conclusively the effect of Guibi-tang on psoriasis cure.

Fig. 1.
before treatment (2013-11-11)
Fig. 2.
after 18 days (2013-11-29)
Fig. 3.
after 36 days (2013-12-17)
Fig. 4.
after 86 days (2014-03-04)
Fig. 5.
before treatment (2014-01-10)
Fig. 6.
after treatment (2014-02-15)
Table 1.
Variation of ISI Score
Before Treatment After 18 days After 36 days After 86 days
ISI Score 27 14 7 2
Table 2.
PASI Score of Case 1
Before Treatment After Treatment
Head 2×(3+3+3)×0.1=1.8 0×(0+0+0)×0.1=0
Trunk 2×(2+2+3)×0.3=4.2 1×(1+0+1)×0.3=0.6
Upper E. 2×(2+2+3)×0.2=2.8 1×(1+0+0)×0.2=0.2
Lower E. 2×(2+3+3)×0.4=6.4 1×(1+0+0)×0.4=0.4
PASI Score 15.2 1.2
Table 3.
Variation of ISI Score
Before Treatment After 25 days After 36 days
ISI Score 21 14 6
Table 4.
PASI Score of Case 2
Before Treatment After Treatment
Head 3×(2+2+2)×0.1=1.8 0×(0+0+0)×0.1=0
Trunk 2×(2+2+2)×0.3=3.6 1×(1+0+1)×0.3=0.6
Upper E. 2×(2+3+2)×0.2=2.8 1×(1+0+1)×0.2=0.4
Lower E. 2×(2+3+3)×0.4=6.4 1×(1+0+1)×0.4=0.8
PASI Score 14.6 1.8


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